biglycan


bi·gly·can

(bī'glī-kan), [MIM*301870] A small interstitial proteoglycan that contains two glycosaminoglycan chains. Synonym(s): proteoglycan I

biglycan

A small leucine-rich repeat (LRR) proteoglycan encoded by BGN on chromosome Xq28, which plays a role in assembly of collagen fibrils and muscle regeneration. It interacts with alpha-dystroglycan, alpha- and gamma-sarcoglycan and collagen VI, and it is critical for the assembly of the dystrophin-associated protein complex.