noradrenaline reuptake inhibitor


noradrenaline reuptake inhibitor

One of a class of drugs that function by increasing the available amount of the neurotransmitter NORADRENALINE at synapses. This is achieved by interfering with the normal physiological reuptake mechanism that brings about the removal of noradrenaline from the synaptic gap. Selective noradrenaline reuptake inhibitors can have a useful antidepressive effect. They include AMITRIPTYLINE, CLOMIPRAMINE, DOXEPIN, IMIPRAMINE, AMOXAPINE, MAPROTILINE and NORTRIPTYLINE.