nephrotic syndrome type 4

A hereditary renal disorder (OMIM:256370) characterised clinically by proteinuria, hypoalbuminaemia, hyperlipidaemia and oedema, and pathologically by focal segmental glomerulosclerosis and diffuse mesangial sclerosis, hypertrophic and vacuolised podocytes, thickened basement membranes, and reduced patency of the capillary lumen. Some patients respond poorly to steroids and progress to end-stage renal failure.
Molecular pathology
Caused by defects of WTI, which encodes a transcription factor that plays an essential role in the normal development of the urogenital system.

单词	nephrotic syndrome type 4
释义	nephrotic syndrome type 4 nephrotic syndrome type 4 A hereditary renal disorder (OMIM:256370) characterised clinically by proteinuria, hypoalbuminaemia, hyperlipidaemia and oedema, and pathologically by focal segmental glomerulosclerosis and diffuse mesangial sclerosis, hypertrophic and vacuolised podocytes, thickened basement membranes, and reduced patency of the capillary lumen. Some patients respond poorly to steroids and progress to end-stage renal failure. Molecular pathology Caused by defects of WTI, which encodes a transcription factor that plays an essential role in the normal development of the urogenital system.
随便看	intermediate unit holder intermediate upper stage intermediate uveitis intermediate value intermediate value theorem intermediate variable intermediate vastus (muscle) intermediate vastus muscle intermediate vector boson intermediate vein of forearm intermediate velocity cloud intermediate vertex intermediate vision intermediate visual and auditory intermediate voltage electron microscopy intermediate-voltage transmission electron microscopy intermediate water intermediate water depth intermediate western boundary current intermediate wheatgrass intermediate white layer ta of superior colliculus intermediate working unit intermedia text intermediate zone intermediate zone of iliac crest