释义 |
DictionarySeediseaseKrabbe's disease
Krabbe's disease [krah´bez] a familial form of leukoencephalopathy beginning in infancy, in which the sphingolipid ceramide galactoside accumulates in the tissues due to a deficiency of β-galactosidase, marked pathologically by cerebral demyelination and by the presence of large globoid bodies in the white substance.Krabbe's disease See GLOBOID CELL LEUKODYSTROPHY. |