Krabbe's disease


Krabbe's disease

 [krah´bez] a familial form of leukoencephalopathy beginning in infancy, in which the sphingolipid ceramide galactoside accumulates in the tissues due to a deficiency of β-galactosidase, marked pathologically by cerebral demyelination and by the presence of large globoid bodies in the white substance.

Krabbe's disease

See GLOBOID CELL LEUKODYSTROPHY.