| Acronym | Definition |
|---|
| OSF➣Oregon Shakespeare Festival (Ashland, Oregon) |
| OSF➣Our Stolen Future (Theo Colborn book) |
| OSF➣Open Society Foundation (New York, NY) |
| OSF➣Open Software Foundation |
| OSF➣Old Spaghetti Factory (US restaurant chain) |
| OSF➣Open System Foundation |
| OSF➣Operations System Function |
| OSF➣One Step Further |
| OSF➣Open Side Flanker |
| OSF➣Orthoptera Species File |
| OSF➣Order of St. Francis (Catholic group) |
| OSF➣Operating System Firmware |
| OSF➣Office of School Facilities (various locations) |
| OSF➣Office of Space Flight |
| OSF➣Ouachita Student Foundation (Arkadelphia, AR) |
| OSF➣Operational Support Facility |
| OSF➣Open Systems Foundation |
| OSF➣Osaka Securities Financing (Japan) |
| OSF➣Optimistes sans Frontieres (French: Optimists without Borders; Belgium) |
| OSF➣Oil Stabilization Fund |
| OSF➣Office of Sustainable Fisheries (National Oceanic and Atmospheric Administration) |
| OSF➣Objective Simulation Framework (US DoD) |
| OSF➣Offset Field |
| OSF➣Operations Support Flight |
| OSF➣Ordinateurs sans Frontieres (French: Computers without Borders) |
| OSF➣Operations System Function (ANSI) |
| OSF➣Off Side Front (automotive suspension) |
| OSF➣Oxidation-induced Stacking Fault |
| OSF➣Open Source Food (est. 2008) |
| OSF➣Oklahoma State Fair, Inc. (Oklahoma City, OK) |
| OSF➣Osaki Sports Foundation (Japan) |
| OSF➣Office of Strategic Finance |
| OSF➣Occupiable Square Feet |
| OSF➣Other Structures and Facilities |
| OSF➣Ordinis Sancti Francisci (of the order of St Francis) |
| OSF➣Open Software Forum |
| OSF➣Office Systems Family |
| OSF➣Ordnance Storage Facility |
| OSF➣Franciscan Brothers or Sisters (religious order) |
| OSF➣Organizational Structure Facility |
| OSF➣Omega Sector Fleetyards (Halo gaming) |
| OSF➣Obtain Service From |
| OSF➣Congregation of Servants of Holy Infancy Jesus (religious order) |
| OSF➣Oversubscription Factor (Cisco) |
| OSF➣Oyster Strike Force |
| OSF➣Ordered Statistics Filter |
| OSF➣On-Site Familiarization |
| OSF➣OpenSSL (Secure Sockets Layer) Software Foundation (Adamstown, MD) |