| 释义 |
morphine
mor·phine M0427000 (môr′fēn′)n. An alkaloid, C17H19NO3, extracted from opium and used in the form of its hydrated sulfate or hydrochloride salt to relieve moderate to severe pain. Also called morphia.
[French, from Morphée, Morpheus, from Latin Morpheus.]morphine (ˈmɔːfiːn) or morphian (Pharmacology) an alkaloid extracted from opium: used in medicine as an analgesic and sedative, although repeated use causes addiction. Formula: C17H19NO3[C19: from French, from Morpheus]mor•phine (ˈmɔr fin) also mor•phi•a (-fi ə)
n. a white, bitter, crystalline alkaloid, C17H19NO3∙H2O, the most important narcotic and addictive principle of opium, obtained by extraction and crystallization and used chiefly in medicine as a pain reliever and sedative. [1820–30; < German Morphin. See Morpheus, -ine2] mor•phin′ic (-ˈfɪn ɪk) adj. mor·phine (môr′fēn′) A drug extracted from opium, used in medicine to relieve severe pain and for its sedative effects. It can be highly addictive.Thesaurus| Noun | 1. | morphine - an alkaloid narcotic drug extracted from opium; a powerful, habit-forming narcotic used to relieve painmorphiaanalgesic, anodyne, pain pill, painkiller - a medicine used to relieve painapomorphine - a morphine derivative that is not as strong as morphine; used as an emetic and in small doses as a sedativeopiate - a narcotic drug that contains opium or an opium derivative |
Translationsmorphine
morphine, principal derivative of opiumopium,
substance derived by collecting and drying the milky juice in the unripe seed pods of the opium poppy, Papaver somniferum. Opium varies in color from yellow to dark brown and has a characteristic odor and a bitter taste.
..... Click the link for more information. , which is the juice in the unripe seed pods of the opium poppypoppy,
common name for some members of the Papaveraceae, a family composed chiefly of herbs of the Northern Hemisphere having a characteristic milky or colored sap. Most species are native to the Old World; many are cultivated in gardens for their brilliantly colored if
..... Click the link for more information. , Papaver somniferum. It was first isolated from opium in 1803 by the German pharmacist F. W. A. Sertürner, who named it after MorpheusMorpheus
, in Greek and Roman mythology, god of dreams. The son of Hypnos (or Somnus), the god of sleep, he brought dreams of human forms. His brothers Phobetor and Phantasos induced dreams of animals and inanimate objects, respectively.
..... Click the link for more information. , the god of dreams. Given intravenously, it is still considered the most effective drug for the relief of pain. See also drug addiction and drug abusedrug addiction and drug abuse,
chronic or habitual use of any chemical substance to alter states of body or mind for other than medically warranted purposes. Traditional definitions of addiction, with their criteria of physical dependence and withdrawal (and often an underlying
..... Click the link for more information. . Effects and Uses Morphine, a narcoticnarcotic,
any of a number of substances that have a depressant effect on the nervous system. The chief narcotic drugs are opium, its constituents morphine and codeine, and the morphine derivative heroin.
See also drug addiction and drug abuse.
..... Click the link for more information. , acts directly on the central nervous system. Besides relieving pain, it impairs mental and physical performance, relieves fear and anxiety, and produces euphoria. It also decreases hunger, inhibits the cough reflex, produces constipation, and usually reduces the sex drive; in women it may interfere with the menstrual cycle. Morphine is highly addictive. Tolerance (the need for higher and higher doses to maintain the same effect) and physical and psychological dependence develop quickly. Withdrawal from morphine causes nausea, tearing, yawning, chills, and sweating lasting up to three days. Morphine crosses the placental barrier, and babies born to morphine-using mothers go through withdrawal. Today morphine is used medicinally for severe pain, cough suppression, and sometimes before surgery. It is seldom used illicitly except by doctors and other medical personnel who have access to the drug. It is injected, taken orally or inhaled, or taken through rectal suppositories. Methadonemethadone
, synthetic narcotic similar in effect to morphine. Synthesized in Germany, it came into clinical use after World War II. It is sometimes used as an analgesic and to suppress the cough reflex.
..... Click the link for more information. treatment has been useful in curing morphine addiction. History Morphine was first used medicinally as a painkiller and, erroneously, as a cure for opium addiction. It quickly replaced opium as a cure-all recommended by doctors and as a recreational drug and was readily available from drugstores or through the mail. Substitution of morphine addiction for alcohol addiction was considered beneficial by some physicians because alcohol is more destructive to the body and is more likely to trigger antisocial behavior. Morphine was used during the American Civil WarCivil War,
in U.S. history, conflict (1861–65) between the Northern states (the Union) and the Southern states that seceded from the Union and formed the Confederacy.
..... Click the link for more information. as a surgical anesthetic and was sent home with many wounded soldiers for relief of pain. At the end of the war, over 400,000 people had the "army disease," morphine addiction. The Franco-Prussian War in Europe had a similar effect. In 1906 the Pure Food and Drug Act required accurate labeling of patent medicines and tonics. Various laws restricting the importation of opium were enacted, and the Harrison Narcotics Act (1914) prohibited possession of narcotics unless properly prescribed by a physician. Despite legislation, morphine maintained much of its popularity until heroinheroin
, opiate drug synthesized from morphine (see narcotic). Originally produced in 1874, it was thought to be not only nonaddictive but useful as a cure for respiratory illness and morphine addiction, and capable of relieving morphine withdrawal symptoms.
..... Click the link for more information. came into use, it in its turn believed to be a cure for morphine addiction. Bibliography See publications of the Drugs & Crime Data Center and Clearinghouse, the Bureau of Justice Statistics Clearinghouse, and the National Clearinghouse for Alcohol and Drug Information. Morphine an alkaloid of opium, a medicinal preparation of the group of analgesics. Morphine hydrochloride is prescribed by physicians to relieve pain resulting from injuries and severe pain accompanying various diseases. It is also used in preparing a patient for surgery and in the postoperative period. Morphine is sometimes used to alleviate severe dyspnea owing to cardiac insufficiency. The prolonged use of morphine may result in addiction to the drug. morphine[′mȯr‚fēn] (pharmacology) C17H19NO3·H2O A white crystalline narcotic powder, melting point 254°C, an alkaloid obtained from opium; used in medicine in the form of a hydrochloride or sulfate salt. morphine, morphia an alkaloid extracted from opium: used in medicine as an analgesic and sedative, although repeated use causes addiction. Formula: C17H19NO3 morphine
morphine [mor´fēn] the principal and most active opium alkaloid, an analgesic" >opioid analgesic and respiratory depressant, usually used as the sulfate salt and administered orally, parenterally, or rectally. It is used as an analgesic for relief of severe pain, antitussive, adjunct to anesthesia, and adjunct to treatment of pulmonary edema caused by left ventricular failure. Its use carries with it the dangers of addiction (see drug dependence), as well as tolerance" >drug tolerance (the need for increasingly larger doses over time to achieve the desired effect). Since morphine is a powerful respiratory depressant, it should be withheld and the patient carefully assessed if the patient's respirations are less than 12 per minute.mor·phine (mōr'fēn, mōr-fēn'), The major phenanthrene alkaloid of opium; it produces a combination of depression and excitation in the central nervous system and some peripheral tissues; predominance of either central stimulation or depression depends on the species and dose; repeated administration leads to the development of tolerance, physical dependence, and (if abused) psychic dependence. Used as an analgesic, sedative, and anxiolytic. [L. Morpheus, god of dreams or of sleep] morphine (môr′fēn′)n. An alkaloid, C17H19NO3, extracted from opium and used in the form of its hydrated sulfate or hydrochloride salt to relieve moderate to severe pain. Also called morphia.morphine An opium alkaloid with potent analgesic effect that owes its narcotic properties to its unique aromatic ring structure.
Clinical findings
Euphoria, respiratory depression, drowsiness, nausea, vomiting, decreased GI motility, increased risk of addiction.
Route
Parenteral, oral.
Effects
Blocks pain signals to brain and spinal cord.
Uses
Relieves severe acute and chronic pain; facilitates induction of anaesthesia.morphine Pain management An opium alkaloid with potent analgesic effect that owes its narcotic properties to its particular aromatic ring structure Route Parenteral, oral Effects Blocks pain signals to brain and spinal cord Uses Relieves severe acute and chronic pain; facilitates induction of anesthesia Clinical Euphoria, respiratory depression, drowsiness, N&V, ↓ GI motility, risk of addiction, miosis. See Controlled drug substances, Designer drugs, Heroin, Substance abuse. mor·phine (mōr'fēn) The major phenanthrene alkaloid of opium, which contains 9-14% of anhydrous morphine. It produces a combination of depression and excitation in the central nervous system and some peripheral tissues; predominance of either central stimulation or depression depends on the species and dose; repeated administration leads to the development of tolerance, physical dependence, and (in instances of abuse) psychic dependence. Used as an analgesic, sedative, and anxiolytic. Classified as a U.S. Schedule II controlled medication. [L. Morpheus, god of dreams and sleep]morphine A powerful pain-killing and narcotic drug used to control persistent pain that cannot be relieved by lesser drugs. It can be taken by mouth or given by injection. Morphine has a valuable effect on the emotional response to pain and in relieving the anxiety associated with the contemplation of the implications of severe pain. It is a respiratory depressant and is never given in cases of head injury or in other conditions in which respiration may be prejudiced. When appropriately prescribed addiction is unlikely. The drug is on the WHO official list. Brand names are Morcap SR, MST Continus, MXL, Oramorph, Sevredol and Zomorph. The drug is also formulated with the anti-emetic cyclizine under the brand name Cyclimorph.morphine a white, crystalline, narcotic alkaloid drug obtained from opium. Formula: C17H19NO3MorphineMorphine is the naturally occurring opioid in the opium poppy, Papaver somniferum. It is a powerful narcotic analgesic, and its primary clinical use is in the management of moderately severe to severe pain. After heroin, morphine has the greatest potential for addiction of all narcotic analgesics.Mentioned in: Methadonemor·phine (mōr'fēn) The major phenanthrene alkaloid of opium. Used as an analgesic, sedative, and anxiolytic. [L. Morpheus, god of dreams and sleep]morphine
Related to morphine: Morphine sulfateSynonyms for morphinenoun an alkaloid narcotic drug extracted from opiumSynonymsRelated Words- analgesic
- anodyne
- pain pill
- painkiller
- apomorphine
- opiate
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