maturation inhibitor

An antiretroviral agent that inhibits viral replication by disrupting late Gag processing, which is required for the structural rearrangement of viral maturation, a key step in the maturation of viral particles into mature, infectious virions.
Maturation inhibitors (e.g., PA-457) prevent virus maturation by interrupting the conversion of the capsid precursor (p25) to a mature capsid protein (p24), resulting in the formation of defective, noninfectious virus particles.

单词	maturation inhibitor
释义	maturation inhibitor maturation inhibitor An antiretroviral agent that inhibits viral replication by disrupting late Gag processing, which is required for the structural rearrangement of viral maturation, a key step in the maturation of viral particles into mature, infectious virions. Maturation inhibitors (e.g., PA-457) prevent virus maturation by interrupting the conversion of the capsid precursor (p25) to a mature capsid protein (p24), resulting in the formation of defective, noninfectious virus particles.
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