NSAID enteropathy
NSAID enteropathy
A general term for small intestinal disease that develops in up to 2/3 of patients receiving long-term NSAIDs, 10% of whom have evidence of small bowel ulceration at autopsy; COX-2 inhibitors are somewhat protective.Clinical findings
Intestinal inflammation; occult blood loss; protein-losing enteropathy; iron deficiency due in part to nonspecific small intestinal ulceration—in particular of the jejunum and ileum—with haemorrhage and perforation, intestinal strictures anoccidia stenoses.