NSAID enteropathy

NSAID enteropathy

A general term for small intestinal disease that develops in up to 2/3 of patients receiving long-term NSAIDs, 10% of whom have evidence of small bowel ulceration at autopsy; COX-2 inhibitors are somewhat protective.
 
Clinical findings
Intestinal inflammation; occult blood loss; protein-losing enteropathy; iron deficiency due in part to nonspecific small intestinal ulceration—in particular of the jejunum and ileum—with haemorrhage and perforation, intestinal strictures anoccidia stenoses.

NSAID enteropathy

An enteropathy induced by NSAIDs Clinical Intestinal inflammation, occult blood loss, protein-losing enteropathy, iron-deficiency due in part to nonspecific small intestinal ulceration–in particular of the jejunum and ileum, with hemorrhage and perforation, intestinal strictures, ileal stenoses. See Nonsteroidal anti-inflammatory drug.