| 释义 |
bioassay
bi·o·as·say B0260200 (bī′ō-ăs′ā′, -ă-sā′)n.1. Determination of the strength or biological activity of a substance, such as a drug, by comparing its effects with those of a standard preparation on a test organism.2. A test used to determine such strength or activity.tr.v. bi·o·as·sayed, bi·o·as·say·ing, bi·o·as·says To cause to undergo a bioassay.bioassay n (Biochemistry) a method of determining the concentration, activity, or effect of a change to substance by testing its effect on a living organism and comparing this with the activity of an agreed standard vb (Biochemistry) (tr) to subject to a bioassay bi•o•as•say (n. ˌbaɪ oʊ əˈseɪ, -ˈæs eɪ; v. ˌbaɪ oʊ əˈseɪ)
n. 1. determination of the biological activity or potency of a substance, as a vitamin or hormone, by testing its effect on the growth of an organism. v.t. 2. to subject to a bioassay. [1910–15] bioassay
Past participle: bioassayed
Gerund: bioassaying
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| bioassay | | bioassay |
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| I bioassay | | you bioassay | | he/she/it bioassays | | we bioassay | | you bioassay | | they bioassay |
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| I bioassayed | | you bioassayed | | he/she/it bioassayed | | we bioassayed | | you bioassayed | | they bioassayed |
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| I am bioassaying | | you are bioassaying | | he/she/it is bioassaying | | we are bioassaying | | you are bioassaying | | they are bioassaying |
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| I have bioassayed | | you have bioassayed | | he/she/it has bioassayed | | we have bioassayed | | you have bioassayed | | they have bioassayed |
| Past Continuous |
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| I was bioassaying | | you were bioassaying | | he/she/it was bioassaying | | we were bioassaying | | you were bioassaying | | they were bioassaying |
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| I had bioassayed | | you had bioassayed | | he/she/it had bioassayed | | we had bioassayed | | you had bioassayed | | they had bioassayed |
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| I will bioassay | | you will bioassay | | he/she/it will bioassay | | we will bioassay | | you will bioassay | | they will bioassay |
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| I will have bioassayed | | you will have bioassayed | | he/she/it will have bioassayed | | we will have bioassayed | | you will have bioassayed | | they will have bioassayed |
| Future Continuous |
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| I will be bioassaying | | you will be bioassaying | | he/she/it will be bioassaying | | we will be bioassaying | | you will be bioassaying | | they will be bioassaying |
| Present Perfect Continuous |
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| I have been bioassaying | | you have been bioassaying | | he/she/it has been bioassaying | | we have been bioassaying | | you have been bioassaying | | they have been bioassaying |
| Future Perfect Continuous |
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| I will have been bioassaying | | you will have been bioassaying | | he/she/it will have been bioassaying | | we will have been bioassaying | | you will have been bioassaying | | they will have been bioassaying |
| Past Perfect Continuous |
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| I had been bioassaying | | you had been bioassaying | | he/she/it had been bioassaying | | we had been bioassaying | | you had been bioassaying | | they had been bioassaying |
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| I would bioassay | | you would bioassay | | he/she/it would bioassay | | we would bioassay | | you would bioassay | | they would bioassay |
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| I would have bioassayed | | you would have bioassayed | | he/she/it would have bioassayed | | we would have bioassayed | | you would have bioassayed | | they would have bioassayed |
Thesaurus| Noun | 1. | bioassay - appraisal of the biological activity of a substance by testing its effect on an organism and comparing the result with some agreed standardbio-assayassay - a quantitative or qualitative test of a substance (especially an ore or a drug) to determine its components; frequently used to test for the presence or concentration of infectious agents or antibodies etc.immunoassay, immunochemical assay - identification of a substance (especially a protein) by its action as an antigen; "PSA in the blood can be measured with an immunochemical assay"pregnancy test - a physiological test to determine whether a woman is pregnant | | Verb | 1. | bioassay - subject to a bio-assayassay - analyze (chemical substances) |
Translationsbioassay
Bioassay A method for the quantitation of the effects on a biological system by its exposure to a substance, as well as the quantitation of the concentration of a substance by some observable effect on a biological system. The biological material in which the effect is measured can range from subcellular components and microorganisms to groups of animals. The substance can be stimulatory, such as an ion increasing taxis behavior in certain protozoans, or inhibitory, such as an antibiotic for bacterial growth. Bioassays are most frequently used when there is a number of steps, usually poorly understood, between the substance and the behavior observed, or when the substance is a complex mixture of materials and it is not clear what the active components are. Bioassays can be replaced, in time, by either a more direct measure of concentration of the active principle, such as an analytical method (for example, mass spectrometry, high-pressure liquid chromatography, radioimmunoassay), or a more direct measurement of the effect, such as binding to a surface receptor in the case of many drugs, as the substance or its mechanism of action is better characterized. Assays to quantitate the effects of an exposure model the effect of a substance in the real world. Complex biological responses can be estimated by laboratory culture tests, which use, for example, bacteria or cells cultured in a petri dish (usually to model an effect either on the organism of interest, such as bacteria, or on some basic cellular function); by tissue or organ culture, which isolates pieces of tissue or whole organs in a petri dish (usually to model organ function); or in whole animals (usually to model complex organismic relationships). bioassay[¦bī·ō′as‚ā] (analytical chemistry) A method for quantitatively determining the concentration of a substance by its effect on the growth of a suitable animal, plant, or microorganism under controlled conditions. bioassay
bioassay [bi″o-as´a] determination of the active power of a drug sample by comparing its effects on a live animal or an isolated organ preparation with those of a reference standard.bi·o·as·say (bī'ō-as'ā), Determination of the potency or concentration of a compound by its effect on animals, isolated tissues, or microorganisms, as compared with an analysis of its chemical or physical properties.bioassay (bī′ō-ăs′ā′, -ă-sā′)n.1. Determination of the strength or biological activity of a substance, such as a drug, by comparing its effects with those of a standard preparation on a test organism.2. A test used to determine such strength or activity.tr.v. bioas·sayed, bioas·saying, bioas·says To cause to undergo a bioassay.bioassay Lab medicine
Any quantification procedure to detect:
(1) The activity or potency—functional or effective—amount of a substance—e.g., antibiotic, chemical, drug, hormone, metabolit, vitamin, etc.—in a biological fluid;
(2) Toxicity of a substance (e.g., a pollutant) or organism (e.g., a pathogen) of interest in an in vivo system, i.e., in a cell or animal; in bioassays, the effect is tested on living cells or organisms.
Molecular biology
An assay that uses a living system, such as an intact cell, to measure an effect or a molecule of interest.
Radiation physics
A determination of the quantity of radioactive material in the human body, either by direct measurement—in vivo counting—or by analysis of excreta.bi·o·as·say (bī'ō-as'ā) Determination of the potency or concentration of a compound by its effect on animals, isolated tissues, or microorganisms, as contrasted with analysis of its chemical or physical properties.
Synonym(s): biologic assay, biotest. bioassay A method of measuring the potency of a drug or other biochemical agent by comparing its effects on animals with those of known preparations of standard strength.bioassay
Synonyms for bioassaynoun appraisal of the biological activity of a substance by testing its effect on an organism and comparing the result with some agreed standardSynonymsRelated Words- assay
- immunoassay
- immunochemical assay
- pregnancy test
verb subject to a bio-assayRelated Words |