micromegakaryocyte

micromegakaryocyte

A small platelet precursor with agranular cytoplasm, hyalinoplasmic zones (pseudopods), a rounded, dense nucleus and 1–3 small nucleoli, which is associated with large atypical platelets. Micromegakaryocytes often indicate abnormal megakaryopoiesis and associated myeloproliferative disorders, such as chronic idiopathic myelofibrosis (agnogenic myeloid metaplasia), a blast crisis of CML.