| 单词 | temazepam | |||
| 释义 | temazepamenUKte·maz·e·pamT0096450 (tə-măz′ə-păm′)temazepam(təˈmæzəˌpæm)
temazepamenUKtemazepamtemazepamenUKtemazepam[tĕ-maz´ĕ-pam]temazepamPharmacologic class: Benzodiazepine Therapeutic class: Sedative-hypnotic Controlled substance schedule IV Pregnancy risk category X ActionDepresses CNS at limbic, thalamic, and hypothalamic levels. Enhances effects of gamma-aminobutyric acid, resulting in sedation, hypnosis, skeletal muscle relaxation, and anticonvulsant and anxiolytic activity. AvailabilityCapsules: 7.5 mg, 15 mg, 22.5 mg, 30 mg Indications and dosages➣ Insomnia Adults: 15 mg P.O. at bedtime p.r.n. Range is 7.5 to 30 mg. Dosage adjustment• Elderly or debilitated patients Contraindications• Hypersensitivity to drug or other benzodiazepines • Pregnancy PrecautionsUse cautiously in: • chronic pulmonary insufficiency, hepatic dysfunction, renal disease, psychoses, drug abuse • history of suicide attempt or drug abuse • elderly or debilitated patients • breastfeeding patients • children younger than age 15. Administration• Give at bedtime with or without food.  Adverse reactionsCNS: hangover, headache, dizziness, drowsiness, lethargy, fatigue, paradoxical stimulation, light-headedness, talkativeness, irritability, nervousness, confusion, euphoria, relaxed feeling, tremor, incoordination, impaired memory, nightmares, paresthesia CV: chest pain, palpitations, tachycardia EENT: eye irritation, pain, and swelling; photophobia; tinnitus GI: nausea, vomiting, constipation, diarrhea, heartburn, abdominal pain, dry mouth, anorexia Musculoskeletal: joint pain Other: altered taste, body pain, physical or psychological drug dependence, drug tolerance InteractionsDrug-drug. Antidepressants, antihistamines, opioid analgesics, other sedative-hypnotics: additive CNS depression Digoxin: increased digoxin blood level, greater risk of toxicity Probenecid: faster temazepam onset and prolonged effects Theophylline: antagonism of temazepam's sedative effects Drug-herbs. Chamomile, hops, kava, skullcap, valerian: increased CNS depression Drug-behaviors. Alcohol use: additive CNS depression Smoking: increased drug metabolism Patient monitoring• Monitor neurologic status carefully. Check for paradoxical reactions, especially in elderly patient. • Watch for signs and symptoms of physical and psychological drug dependence. Stay alert for drug hoarding. Patient teaching• Advise patient to establish effective bedtime routine, to minimize insomnia. • Inform patient (and significant other if appropriate) that drug may cause psychological and physical dependence and should be used only as prescribed and needed. • Caution patient to avoid driving and other hazardous activities on day after taking drug, until he knows how it affects concentration and alertness. • Instruct patient not to drink alcohol. • Advise patient not to smoke or use herbs without consulting prescriber. • Instruct patient to report suspected pregnancy. • As appropriate, review all other significant adverse reactions and interactions, especially those related to the drugs, herbs, and behaviors mentioned above. temazepam(tə-măz′ə-păm′)temazepamTemaze Pharmacology A benzodiazepine used for insomnia. See Benzodiazepine.temazepamA benzodiazepine drug used to treat insomnia. A brand name is Normison.temazepamenUK
Synonyms for temazepam
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