| 释义 |
third generation cephalosporin third generation cephalosporin Infectious disease A group of broad-spectrum antibiotics–eg, cefatoxime, ceftazidime, ceftriaxone and moxalactam that are structurally related to penicillins and used against penicillinase-producing bacteria; TGCs are more active against enteric bacteria, are stable against the β-lactamases of H influenzae and N gonorrhoeae, have a longer serum T1/2 than 1st generation cephalosporins– administered twice/day, cross the blood-brain barrier and effective against gram-negative CNS infections |