| 单词 | von willebrand's disease | |||
| 释义 | von Willebrand's diseasevon Wil·le·brand's diseaseV0146750 (vŏn wĭl′ə-brăndz′, fôn vĭl′ə-bränts′)
von Willebrand's diseasevon Willebrand's disease[von vil´ĕ-brahnts]von Willebrand's diseaseA rare group of hereditary bleeding disorders, similar to HAEMOPHILIA but usually less sevee, due to deficiency of a clotting factor necessary for PLATELET adhesion to blood vessel walls and as a carrier for Factor VIII. The condition is usually inherited as an autosomal dominant and, unlike haemophilia, occurs equally in both sexes. Some cases are automal recessive. The mutations, which are many, are on the short arm of chromosome 12. The von Willebrand factor (vWF) is a protein, the levels of which are raised in pregnancy. (E. A. von Willebrand, 1870–1949, Swedish physician).von Willebrand's diseasevon Willebrand's disease
Synonyms for von Willebrand's disease
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von Willebrand's disease - a form of hemophilia discovered by Erik von Willebrand; a genetic disorder that is inherited as an autosomal recessive trait; characterized by a deficiency of the coagulation factor and by mucosal bleeding