posttransplantation lymphoproliferative disorder

posttransplantation lymphoproliferative disorder

A complication of 1-10% of organ transplant recipients, which may be poly- or monoclonal; most affected cells contain EBV, usually latent; post-transplantation Pts at risk for PTLD can be identified by detecting expression–as small mRNA of the EBER-1 gene; most cases that occur in solid organ recipients are of host origin