| 释义 |
tricyclic antidepressant
tricyclic antidepressantn. Abbr. TCA Any of a group of antidepressant drugs, such as amitryptyline, that contain three fused benzene rings and that block the reuptake of the neurotransmitters norepinephrine and serotonin in the central nervous system.Thesaurus| Noun | 1. | tricyclic antidepressant - an antidepressant drug that acts by blocking the reuptake of norepinephrine and serotonin and thus making more of those substances available to act on receptors in the braintricyclic, tricyclic antidepressant drugamitriptyline, amitriptyline hydrochloride, Elavil - a tricyclic antidepressant drug (trade name Elavil) with serious side effects; interacts with many other medicationsantidepressant, antidepressant drug - any of a class of drugs used to treat depression; often have undesirable side effectsclomipramine - a tricyclic antidepressant drugdesipramine - a tricyclic antidepressant drug that activates the psychomotor systemAdapin, doxepin, doxepin hydrochloride, Sinequan - a tricyclic antidepressant (trade names Adapin and Sinequan) with numerous side effects (dry mouth and sedation and gastrointestinal disturbances)Imavate, imipramine, impramine hydrochloride, Tofranil - a tricyclic antidepressant (trade names Imavate and Tofranil) used to treat clinical depressionnortriptyline, Pamelor - a tricyclic antidepressant drug (trade name Pamelor) used along with psychotherapy to treat dysthymic depression; may interact dangerously if taken with other drugsprotriptyline - tricyclic antidepressant used to treat clinical depressionSurmontil, trimipramine - tricyclic antidepressant drug (trade name Surmontil) used to treat depression and anxiety and (sometimes) insomnia |
EncyclopediaSeeTCAtricyclic antidepressant
tri·cyc·lic an·ti·de·pres·santa chemical group of antidepressant drugs that share a three-ringed nucleus.tricyclic antidepressantn. Abbr. TCA Any of a group of antidepressant drugs, such as amitryptyline, that contain three fused benzene rings and that block the reuptake of the neurotransmitters norepinephrine and serotonin in the central nervous system.tricyclic antidepressant Pharmacology Any psychoactive dibenzozepine derivative–eg, which have 3 central rings and a short linear chain attached to the terminal nitrogen and are thus tertiary amines Lab TA levels correlate poorly with the clinical status, as circulating levels of the highly lipid-soluble TCA represent a minute portion of the body load, and TCA metabolites with similar clinical effects may not be measured Clinical, overdose Parasympathetic disease with anticholinergic effects–eg, mydriasis, xerostomia, urinary retention, ↓ peristalsis, cardiac disease–intractable myocardial depression, hypotension, ventricular tachycardia, fibrillation, or heart block and CNS disease–confusion, agitation, hallucinations, myoclonus, seizures, lethargy that may progress to coma and respiratory arrest Adverse effects Dry mouth, constipation, blurred vision, hyperthermia, weakness, fatigue, lethargy, insomnia, confusion, seizures, ↓ peristalsis, hypotension, coma. See Desipramine, Imipramine, Nortriptyline, Therapeutic drug monitoring, Tricyclic antidepressant suicide. Cf Fluoxetine, Monoamine oxidase inhibitors. tri·cyc·lic an·ti·de·pres·sant (TCA) (trī-sīklik antē-dĕ-presănt) Chemical group of antidepressant drugs that share a three-ringed nucleus. tri·cyc·lic an·ti·de·pres·sant(TCA) (trī-sīklik antē-dĕ-presănt) Chemical group of antidepressants that share three-ringed nucleus. See TCA
See TCAtricyclic antidepressant
Synonyms for tricyclic antidepressantnoun an antidepressant drug that acts by blocking the reuptake of norepinephrine and serotonin and thus making more of those substances available to act on receptors in the brainSynonyms- tricyclic
- tricyclic antidepressant drug
Related Words- amitriptyline
- amitriptyline hydrochloride
- Elavil
- antidepressant
- antidepressant drug
- clomipramine
- desipramine
- Adapin
- doxepin
- doxepin hydrochloride
- Sinequan
- Imavate
- imipramine
- impramine hydrochloride
- Tofranil
- nortriptyline
- Pamelor
- protriptyline
- Surmontil
- trimipramine
|