| 单词 | ticlopidine |
| 释义 | ticlopidineti·clo·pi·dineT5224350 (tī-klō′pə-dēn′)ticlopidineticlopidine[ti-klo´pĭ-dēn]ticlopidine(tī-klō′pə-dēn′)ticlopidineTherapeutics A platelet aggregation inhibitor that alters the platelet membrane, interfering with membrane-fibrinogen interaction by blocking platelet gpIIb/IIIa receptor Indications ↓ Stroke in high risk Pts, minimize stroke progression, cerebral ischemia, progression of diabetic retinopathy Side effects BM suppression with severe reversible neutropenia, diarrhea, rash, gastritis or gastric ulcers–nausea, dyspepsia, hemorrhage, thrombocytopenia, ↑ cholesterol. See TIA.ticlopidineA thienopyridine drug that interacts with platelet glycoprotein in such a way as to inhibit platelet function. It has been found useful in preventing vein grafts from becoming occluded by thrombosis. |
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