peroxisome proliferator-activated receptor-gamma

A receptor widely expressed in macrophages, which has been identified as a putative target for novel therapies against inflammatory bowel disease (IBD).
PPAR-gamma deletion significantly exacerbates clinical activity and colonic pathology; impairs the splenic and mesenteric lymph node regulatory T-cell compartment; increases percentages of lamina propria (LP) CD8+ T cells; increases surface expression of CD40, Ly6C and Toll-like receptor 4 (TLR-4) in LP macrophages; and upregulates expression of colonic IFN-γ, CXCL9, CXCL10, IL-22, IL1RL1, CCR1 (suppressor of cytokine-signalling 3), and MHC class-II in mice with IBD.

单词	peroxisome proliferator-activated receptor-gamma
释义	peroxisome proliferator-activated receptor-gamma peroxisome proliferator-activated receptor-gamma A receptor widely expressed in macrophages, which has been identified as a putative target for novel therapies against inflammatory bowel disease (IBD). PPAR-gamma deletion significantly exacerbates clinical activity and colonic pathology; impairs the splenic and mesenteric lymph node regulatory T-cell compartment; increases percentages of lamina propria (LP) CD8+ T cells; increases surface expression of CD40, Ly6C and Toll-like receptor 4 (TLR-4) in LP macrophages; and upregulates expression of colonic IFN-γ, CXCL9, CXCL10, IL-22, IL1RL1, CCR1 (suppressor of cytokine-signalling 3), and MHC class-II in mice with IBD.
随便看	genii locorum ge, nikolai ge, nikolai nikolaevich geniko stratiotiko nosokomeio athinon genil -genin genin gen-indapamide geninfo identifier genio genioglossal muscle genioglossi genioglossus genioglossus advancement hyoid myotomy genioglossus (muscle) genioglossus muscle geniohyidae geniohyoglossus geniohyoglossus muscle geniohyoid geniohyoideus geniohyoideus muscle geniohyoid (muscle) geniohyoid muscle geniohyoid tubercle