单词 | prokr1 |
释义 | PROKR1PROKR1A gene on chromosome 2p13.1 that encodes the G protein-coupled receptor for prokineticin 1, one of a family of secreted proteins that promote angiogenesis and induce strong gastrointestinal smooth muscle contraction. PROKR1 is exclusively coupled to the G(q) subclass of heteromeric G proteins; its activation mobilises calcium, stimulates phosphoinositide turnover and activates p44/p42 mitogen-activated protein kinase. |
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