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Vinca alkaloids
Vinca alkaloidsCytotoxic drugs used to prevent the replication of cells.EncyclopediaSeealkaloidvinca alkaloids
vinca alkaloids [vin´kah] a group of cytotoxic alkaloids extracted from the Madagascar periwinkle (Catharanthus roseus G. Don or Vinca rosea L.) and used as antineoplastic agents; they are cell cycle specific for the M phase of cell division and disrupt the microtubules that form the spindle apparatus. The group includes vinblastine, vincristine, vindesine, and vinorelbine tartrate.Vinca al·ka·loidsalkaloids such as vincristine and vinblastine (antitumor agents) extracted from the periwinkle plant. Synonym(s): Catharanthus alkaloidsvinca alkaloids A class of cytotoxic drugs used to treat various cancers. Examples are vindesine (Eldisine), vincristine (Oncovin) and vinblastine (Velbe).ThesaurusSeeCatharanthus |