zonula adherens


zo·nu·la ad·he·'rens

a beltlike attachment, similar to a desmosome, between columnar epithelial cells; supported by cytoplasmic filaments. Synonym(s): intermediate junction

Adherens Junction

A protein complex located at the junction between epithelial cells, which are subjected to stretching and pulling, yet require tight contact between them so they can function as a single unit. Adherens junctions are linked to the cell’s actin cytoskeleton, and take two forms: as bands encircling the cell—zonula adherens—or as “spot welds” to the extracellular matrix—adhesion plaques. Adherens junctions are composed of 4 principle proteins: cadherins and alpha-catenin, plakoglobulin (aka beta or gamma catenin) and p120 (aka delta catenin).

zo·nu·la ad·he·rens

(zōnyū-lă ad-hērenz) Beltlike attachment, similar to a desmosome, between columnar epithelial cells; supported by cytoplasmic filaments. Also called intermediate junction.