Albright hereditary osteodystrophy


Al·bright he·red·i·tar·y os·te·o·dys·tro·phy

(al'brīt), [MIM*103580, MIM*300800, MIM*203330] an inherited form of hyperparathyroidism associated with ectopic calcification, ossification, and skeletal defects, notably in the small fourth metacarpals; intelligence may be normal or subnormal. Inheritance is heterogeneous; the autosomal form [MIM*103580] is caused by mutation in the guanine nucleotide-binding protein gene (GNAS1) on 20q. There are also the recessive [MIM*203330] and X-linked [MIM*300800] forms.
See also: pseudohypoparathyroidism. Synonym(s): Albright syndrome (2)

Al·bright he·red·i·tar·y os·te·o·dys·tro·phy

(awl'brīt hĕr-ed'i-tar-ē os'tē-ō-dis'trŏ-fē) An inherited form of hyperparathyroidism associated with ectopic calcification and ossification and skeletal defects, notably small fourth metacarpals; intelligence may be normal or subnormal. Inheritance is heterogeneous; the autosomal form is caused by mutation in the guanine nucleotide-binding protein gene (GNAS1) on 20q. There are the recessive and X-linked forms.
See also: pseudohypoparathyroidism
Synonym(s): Albright syndrome (2) .

Albright,

Fuller, U.S. physician, 1900-1969. Albright disease - Synonym(s): McCune-Albright syndromeAlbright-Hadorn syndrome - softening and bending of bones associated with abnormally small concentration of potassium in blood.Albright hereditary osteodystrophy - an inherited form of hyperparathyroidism associated with ectopic calcification and ossification and skeletal defects. Synonym(s): Albright syndrome (1)Albright syndrome - (1) Synonym(s): Albright hereditary osteodystrophy - (2) Synonym(s): McCune-Albright syndromeAlbright IV syndrome - Synonym(s): Martin-Albright syndromeAlbright synovectomyForbes-Albright syndrome - see under Forbes, Anne PMartin-Albright syndrome - see under Martin, August EMcCune-Albright syndrome - see under McCune

Al·bright he·red·i·tar·y os·te·o·dys·tro·phy

(awl'brīt hĕr-ed'i-tar-ē os'tē-ō-dis'trŏ-fē) [MIM*103580, 300800, 203330, MIM*103580, 300800, 203330] Inherited form of hyperparathyroidism associated with ectopic calcification, ossification, and skeletal defects.