blastokinin

u·ter·o·glo·bin

(yū'tĕr-ō-glō'bin), [MIM*192020] A steroid-inducible, evolutionarily conserved, homodimeric secreted protein with many biologic activities including a proinflammatory effect, inhibition of soluble lipoprotein-lipase A₂, and chemotaxis of neutrophils and monocytes. It binds to several putative receptors on several cell types and inhibits cellular invasion of the extracellular matrix. It is found in blood and urine, uterus and numerous other tissues, but not kidneys. In mice, uteroglobin has been shown to bind to fibronectin (Fn), preventing Fn self-aggregation and subsequent abnormal tissue deposition, especially in glomeruli. It is essential for maintaining normal renal function in mice. Synonym(s): blastokinin

blastokinin

(blăs″tō-kī′nĭn) A globulin found in the uterine lumen of some mammals near the time of blastocyst implantation.

单词	blastokinin
释义	blastokinin u·ter·o·glo·bin (yū'tĕr-ō-glō'bin), [MIM*192020] A steroid-inducible, evolutionarily conserved, homodimeric secreted protein with many biologic activities including a proinflammatory effect, inhibition of soluble lipoprotein-lipase A₂, and chemotaxis of neutrophils and monocytes. It binds to several putative receptors on several cell types and inhibits cellular invasion of the extracellular matrix. It is found in blood and urine, uterus and numerous other tissues, but not kidneys. In mice, uteroglobin has been shown to bind to fibronectin (Fn), preventing Fn self-aggregation and subsequent abnormal tissue deposition, especially in glomeruli. It is essential for maintaining normal renal function in mice. Synonym(s): blastokinin blastokinin (blăs″tō-kī′nĭn) A globulin found in the uterine lumen of some mammals near the time of blastocyst implantation.
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