Blue Cell Tumour

A usually malignant tumour, the cells of which are arranged in nests, sheets, and masses, and composed of relatively monotonous, round-to-oval, 8–15-µm in diameter cells with poorly defined cytoplasmic borders and strongly basophilic—blue—by H&E staining nuclei; embryologic origin often requires ancillary information provided by histologic pattern, immunohistochemistry, and rarely electron microscopy
DiffDx
Children Neuroblastoma, Ewing sarcoma, NHL, embryonal rhabdomyosarcoma
Adults Neuroendocrine tumour, mesenchymal chondrosarcoma, hemangiopericytoma, large cell lymphomas, Merkel cell tumour, small cell osteosarcoma, small/oat cell carcinoma, alveolar rhabdomyosarcoma