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daunorubicin Translationsdaunorubicin
daunorubicin [daw″no-roo´bĭ-sin] an antitumor antibiotic of the anthracycline family, produced by a strain of Streptomyces coeruleorubidus and having antimitotic, cytotoxic, and immunosuppressive effects. As the hydrochloride salt it is administered intravenously in the treatment of leukemia" >acute lymphoblastic leukemia and leukemia" >acute myelogenous leukemia. As a liposome-encapsulated preparation of the citrate salt, it is administered intravenously in the treatment of advanced sarcoma" >Kaposi's sarcoma associated with acquired immunodeficiency syndrome (AIDS).dau·no·ru·bi·cin (daw'nō-rū'bi-sin), An antineoplastic antibiotic of the rhodomycin group, obtained from Streptomyces peucetius.daunorubicin Oncology An antineoplastic antibiotic isolated from Streptomyces spp, effective against ALL and AML, and used for other CAs Toxicity Dose-related BM suppression, mucositis, alopecia, severe local reaction with extravasationru·bid·o·my·cin (rū-bid'ō-mī'sin) An antibiotic used as an antineoplastic; similar to doxorubicin in antitumor activity and in exhibiting cumulative cardiotoxicity. Synonym(s): daunorubicin. daunorubicin An antibiotic drug used in the consolidation phase of the treatment of acute leukaemia. The drug is on the WHO official list. Brand names are Cerubidin and Daunoxome.dau·no·ru·bi·cin (daw'nō-rū'bi-sin) An anti neoplastic antibiotic of the rhodomycin group, obtained from Streptomyces peucetius. AcronymsSeeDNR |