CD163

A transmembrane protein encoded by CD163 on chromosome 12p13.3, which mediates the endocytosis of haptoglobin-haemoglobin complexes. CD163 belongs to the cysteine-rich scavenger receptor superfamily
Normal expression Highly expressed by tissue macrophages and less so by circulating monocytes. In a soluble form in plasma, it has an anti-inflammatory function.
Abnormal expression Expression is upregulated during inflammation by glucocorticoids, IL-10 and other modulators.

CD163

A cell surface glycoprotein used in immunohistochemistry to identify monocytes and macrophages. See: cluster of differentiation

单词	cd163
释义	CD163 CD163 A transmembrane protein encoded by CD163 on chromosome 12p13.3, which mediates the endocytosis of haptoglobin-haemoglobin complexes. CD163 belongs to the cysteine-rich scavenger receptor superfamily Normal expression Highly expressed by tissue macrophages and less so by circulating monocytes. In a soluble form in plasma, it has an anti-inflammatory function. Abnormal expression Expression is upregulated during inflammation by glucocorticoids, IL-10 and other modulators. CD163 A cell surface glycoprotein used in immunohistochemistry to identify monocytes and macrophages. See: cluster of differentiation
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