bronchopulmonary sequestration
bron·cho·pul·mo·nar·y se·ques·tra·tion
bronchopulmonary sequestration
A rare congenital condition related to developmental defects of the embryonic foregut, in which nonfunctioning lung tissue is detached from the normal lung and does not communicate with the bronchopulmonary tree. Sequestered lung tissue is supplied by an anomalous systemic artery—usually arising from the aorta or a tributary—and contains normal elements in a disorderly array with variable amounts of cartilage, alveolar parenchyma and bronchial glands, the secretion from which leads to the formation of fluid-filled cysts. Communication with functional pulmonary tissue explains the common bacterial infections (although there is considerable overlap in the types).Bronchopulmonary sequestration
Intralobar—85% of cases, bilateral, often supplied by a branch of the thoracic aorta.
Extralobar—More common in men, linked to other congenital defects, may communicate with the foregut; 90% are left sided.