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cefuroxime
cef·ur·ox·ime C5190350 (sĕf′yo͝or-ŏk′sēm′)n. A broad-spectrum cephalosporin antibiotic, C16H16N4O8S, given orally or parenterally to treat a variety of bacterial infections, including early Lyme disease.
[cefur- (blend of ceph(alosporin) and fur(an)) + ox(y)- + alteration of imino (influenced by -ine or -ide).]Thesaurus| Noun | 1. | cefuroxime - a cephalosporin that can be given parenterally (trade name Zinacef) or orally by tablets (trade name Ceftin); indicated for infections of the lungs or throat or ears or urinary tract or meningesCeftin, Zinacefcephalosporin, Mefoxin - one of several broad spectrum antibiotic substances obtained from fungi and related to penicillin (trade names Mefoxin); addition of side chains has produced semisynthetic antibiotics with greater antibacterial activity |
TranslationsEncyclopediaSeeantibioticcefuroxime
cefuroxime [sef″u-rok´sēm] a semisynthetic, β-lactamase–resistant, second-generation cephalosporinantibiotic effective against a wide range of gram-positive and gram-negative bacteria; used as the sodium salt and the axetil ester.cefuroxime (sĕf′yə-rŏk′sēm′)n. A broad-spectrum cephalosporin antibiotic given orally and parenterally for respiratory, skin, and other infections.cefuroxime A second-generation CEPHALOSPORIN antibiotic active against staphylococci and some Gram-negative organisms. It must be given by injection. Brand names are Zinacef and Zinnat.antibiotic 1. Pertaining to the ability to destroy or inhibit other living organisms. 2. A substance derived from a mould or bacterium, or produced synthetically, that destroys (bactericidal) or inhibits the growth (bacteriostatic) of other microorganisms and is thus used to treat infections. Some substances have a narrow spectrum of activity whereas others act against a wide range of both gram-positive and gram-negative organisms (broad-spectrum antibiotics). Antibiotics can be classified into several groups according to their mode of action on or within bacteria: (1) Drugs inhibiting bacterial cell wall synthesis, such as bacitracin, vancomycin and the β-lactams based agents (e.g. penicillin, cephalosporins (e.g. ceftazidime, ceftriaxone, cefuroxime). (2) Drugs affecting the bacterial cytoplasmic membrane, such as polymyxin B sulfate and gramicidin. (3) Drugs inhibiting bacterial protein synthesis, such as aminoglycosides (e.g. amikacin sulfate, framycetin sulfate, gentamicin, neomycin sulfate and tobramycin), tetracyclines, macrolides (e.g. erythromycin and azithromycin) and chloramphenicol. (4) Drugs inhibiting the intermediate metabolism of bacteria, such as sulfonamides (e.g. sulfacetamide sodium) and trimethoprim. (5) Drugs inhibiting bacterial DNA synthesis, such as nalixidic acid and fluoroquinolones (e.g. ciprofloxacin, levofloxacin, moxifloxacin, norfloxacin and ofloxacin). (6) Other antibiotics such as fusidic acid, the diamidines, such as propamidine isethionate and dibrompropamidine. Syn. antibacterial. See antiinflammatory drug; fusidic acid.cefuroxime
Related to cefuroxime: Cefuroxime axetil, CefiximeSynonyms for cefuroximenoun a cephalosporin that can be given parenterally (trade name Zinacef) or orally by tablets (trade name Ceftin)SynonymsRelated Words |