| 释义 |
dedifferentiation
de·dif·fer·en·ti·a·tion D0084000 (dē′dĭf-ə-rĕn′shē-ā′shən)n. Biology Reversion of a specialized cell or tissue to an unspecialized form. Dedifferentiation may occur before the regeneration of appendages in plants and certain animals and in the development of some cancers.
de′dif·fer·en′ti·ate′ v.dedifferentiation (diːˌdɪfəˌrɛnʃɪˈeɪʃən) n (Biology) the reversion of the cells of differentiated tissue to a less specialized formde•dif•fer•en•ti•a•tion (diˌdɪf əˌrɛn ʃiˈeɪ ʃən)
n. Biol. the loss of specialized form or condition previously acquired during development. [1915–20] de`dif•fer•en′ti•ate`, v.i. -at•ed, -at•ing. Thesaurus| Noun | 1. | dedifferentiation - the loss of specialization in form or functionadaption, adaptation, adjustment - the process of adapting to something (such as environmental conditions) |
dedifferentiation
dedifferentiation[dē‚dif·ə‚ren·chē′ā·shən] (biology) Disintegration of a specialized habit or adaptation. (cell and molecular biology) Loss of recognizable specializations that define a differentiated cell. (physiology) Return of a specialized cell or structure to a more general or primitive condition. dedifferentiation
anaplasia [an″ah-pla´zhah] loss of differentiation of cells and their orientation to each other, a characteristic of tumor cells; called also dedifferentiation and undifferentiation.de·dif·fer·en·ti·a·tion (dē-dif'ĕr-en'shē-ā'shŭn), 1. The return of parts to a more homogeneous state. 2. Synonym(s): anaplasiadedifferentiation (dē′dĭf-ə-rĕn′shē-ā′shən)n. Biology Reversion of a specialized cell or tissue to an unspecialized form. Dedifferentiation may occur before the regeneration of appendages in plants and certain animals and in the development of some cancers.
de′dif·fer·en′ti·ate′ v.dedifferentiation Pathology
The reversion of a cell or cell line to a more embryonic form.
Tumour biology
The loss of the cellular features of terminal differentiation, a finding often associated with increased aggressiveness of a neoplasm.de·dif·fer·en·ti·a·tion (dē-dif'ĕr-en'shē-ā'shŭn) 1. The return of parts to a more homogeneous state. 2. Synonym(s): anaplasia. dedifferentiation a process in which tissues that have undergone CELL DIFFERENTIATION can be made to reverse the process so as to become a primordial cell again (see GURDON). In theory, all cells should possess this ability since the mature cell does not lose DNA (see TOTIPOTENCY), but reversal has been demonstrated in plants much more easily than in animal cells.dedifferentiation
Words related to dedifferentiationnoun the loss of specialization in form or functionRelated Words- adaption
- adaptation
- adjustment
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