Balkan nephropathy

Bal·kan ne·phrop·a·thy

interstitial chronic nephritis of unknown etiology, originally described as an endemic disease in the Balkans, characterized by insidious onset, scanty urinary findings, anemia, and acidosis. Synonym(s): danubian endemic familial nephropathy

A chronic tubulointerstitial nephropathy endemic to the littoral regions of the Danube, occurring in the Balkans—Bulgaria, Croatia, Romania, Serbia
Etiology Unknown; converging lines of evidence suggest a link to long-term consumption of food contaminated with aristolochic acid
Prognosis The natural course of the disease is characterised by universal development of end-stage renal disease and the frequent development of upper urinary tract tumours; most patients die within 10 yrs of onset

Balkan nephropathy

A type of chronic NEPHRITIS occurring in certain rural populations in the central Danube basin on the borders of Bulgaria, Yugoslavia and Romania and affecting 10% to 75% of families. The onset is insidious with protein in the urine, gradual impairment of kidney function, coppery discolouration of the skin and anaemia. The outlook is poor and most affected people die within three years. The cause is unknown but the condition may be due to a toxic fungus that grows on wet maize and other grains.

Balkans,

the countries of the Balkan Peninsula, which include Romania, Bulgaria, and Yugoslavia. Balkan frame - metal frame above a bed which provides for limb suspension, named for the Balkan wars, 1908-1913.Balkan nephrectomyBalkan nephritis - chronic progressive nephritis seen predominantly in Balkan countries.Balkan nephropathy - interstitial nephritis occurring in the Balkan countries.

单词	balkan nephropathy
释义	DictionarySeeBalkans Balkan nephropathy Bal·kan ne·phrop·a·thy interstitial chronic nephritis of unknown etiology, originally described as an endemic disease in the Balkans, characterized by insidious onset, scanty urinary findings, anemia, and acidosis. Synonym(s): danubian endemic familial nephropathy A chronic tubulointerstitial nephropathy endemic to the littoral regions of the Danube, occurring in the Balkans—Bulgaria, Croatia, Romania, Serbia Etiology Unknown; converging lines of evidence suggest a link to long-term consumption of food contaminated with aristolochic acid Prognosis The natural course of the disease is characterised by universal development of end-stage renal disease and the frequent development of upper urinary tract tumours; most patients die within 10 yrs of onset Balkan nephropathy A type of chronic NEPHRITIS occurring in certain rural populations in the central Danube basin on the borders of Bulgaria, Yugoslavia and Romania and affecting 10% to 75% of families. The onset is insidious with protein in the urine, gradual impairment of kidney function, coppery discolouration of the skin and anaemia. The outlook is poor and most affected people die within three years. The cause is unknown but the condition may be due to a toxic fungus that grows on wet maize and other grains. Balkans, the countries of the Balkan Peninsula, which include Romania, Bulgaria, and Yugoslavia. Balkan frame - metal frame above a bed which provides for limb suspension, named for the Balkan wars, 1908-1913.Balkan nephrectomyBalkan nephritis - chronic progressive nephritis seen predominantly in Balkan countries.Balkan nephropathy - interstitial nephritis occurring in the Balkan countries.
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