单词 | dosage compensation |
释义 | dosage compensationdosage compensation[′dō·sij ‚käm·pən‚sā·shən]dosage compensationdosage compensationa genetical mechanism in which ALLELES of a gene automatically regulate the amount of a useful product produced, so that homozygous-dominant GENOTYPES produce the same amount of gene product as heterozygotes. In this way the two genotypes cannot be distinguished. Dosage compensation occurs regularly in female mammals where one X-chromosome in each cell is thought to become inactivated, leading to equal amounts of gene products in males and females. See INACTIVE-X HYPOTHESIS. |
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