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单词 Philadelphia chromosome
释义

Philadelphia chromosome

noun Genetics
An abnormal small chromosome sometimes found in the leucocytes of leukaemia patients.The malignant transformation results from a reciprocal translocation between chromosomes 9 and 22, producing a short chromosome known as the Philadelphia chromosome....
  • CML is caused by the breakage and swapping of chromosomes 9 and 22, which results in a shortened chromosome called the Philadelphia chromosome.
  • CML is caused by the errant swapping of genetic material in bone marrow stem cells that produces an abnormality called the Philadelphia chromosome.
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更新时间:2024/9/23 16:27:58