to have sexual intercourse with (somebody)
to spoil or ruin (something)
Whatever the truth of its still debatable etymology, fuck remains the best-known example of the large vocabulary of slang words equating sexual intercourse with striking or hitting. Briefly acknowledged as standard English in the 16th cent., the word is still primarily taboo, although a growing erosion of linguistic prissiness has rendered such exclusion almost equally honoured in its ever-widening breach — Jonathon Green
fucker noun
[perhaps of Scandinavian origin]