a small roundish area different in colour or texture from the surrounding surface

a dirty mark or stain

a pimple or small blemish on the skin

chiefly Brit, informal a small amount; a bit

a spot of bother

a place or area

a nice spot for a picnic

a noteworthy feature or aspect of something

a high spot of the holiday

a place allocated to a person on a broadcast programme or show; = slot¹ (2)

chiefly NAmer a pip on a playing card, domino, or dice

(used before a noun) on-the-spot

spot coverage of the news

(used before a noun) denoting a system of trading in which goods are paid for and delivered immediately after sale

a spot sale

(used in combinations) a location, aspect, or point

the city's nightspots

(often before a noun) a brief space between broadcast television or radio programmes used for an announcement or advertising

spot announcements

= spotlight¹ (1)

(the spot) in football, = penalty spot

= spot board

to notice or detect (somebody or something hidden or difficult to find)

to single out or identify (somebody or something promising)

to watch for and record the sighting of (wildlife species, trains, etc)

to locate (the enemy's position, etc) accurately

to mark (a material, etc) with spots

spotted with mould

to sully (somebody's reputation)

in billiards, to place (the ball) on its starting point

NAmer to lend (somebody) money

to allow (a rival competitor or team) an advantage in a game

to be susceptible to leaving or receiving stains or discoloration

chiefly Brit (with ‘it’ as subject) to fall lightly in scattered drops

said of an aircraft or pilot: to locate targets