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单词 alamethicin
释义 alamethicin, n. Biochem.|æləˈmɛθɪsɪn|
[f. alamethic-, of unknown origin, (perh. a reference to the predominance of methyl alanine residues in the peptide) + -in1.]
A macrocyclic peptide which is produced by strains of the fungus Trichoderma viride and acts as an ionophore and antibiotic.
1968Nature 24 Feb. 713/1 The electrokinetic and chemical data suggest that six or more alamethicin molecules form either carriers or tubular channels through which ions flow across the membrane.1969New Scientist 17 Apr. 127/2 The macrocyclic peptide alamethicin had a similar effect upon the BLM [sc. bimolecular lipid membrane].1979Nature 15 Nov. 336/2 Alamethicin, a polypeptide of molecular weight ∼2,000, induces voltage-dependent conductance phenomena in artificial lipid bilayer membranes.
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