| 释义 |
Grignard Chem.|ˈgriːnjɑː(r)|
The name of F. A. V. Grignard (1871–1935), French chemist, used attrib. and in the possessive to designate organometallic compounds of magnesium represented by the formula RMgX (where R is an organic radical and X a halogen), and the organic syntheses performed using such compounds; so Grignard('s) compound, Grignard reagent; Grignard('s) reaction.
[1902Jrnl. Chem. Soc. LXXXII. i. 70 The following compounds have been obtained by Grignard's methods.] 1904Ibid. LXXXV. 1666 (heading) The Grignard reaction applied to the esters of hydroxy-acids. Ibid. LXXXVI. i. 38 (heading) Nitric oxide and Grignard's reagent. 1936Discovery May 162/2 Active organic substances (like organo-metallic compounds and the Grignard reagents) which are used as reagents, and the function of anionoid and kationoid reagents in ionic reactions are treated. 1964N. G. Clark Mod. Org. Chem. v. 69 When dissolved in dry ether, and treated with dry magnesium metal, alkyl halides combine to give alkylmagnesium halides or ‘Grignard compounds’. 1966Phillips & Williams Inorg. Chem. II. xxvii. 331 Grignard reagents are also of quite general applicability in substitution reactions of metal halides. |