| 释义 |
Wernicke Path.|v-, ˈwɜːnɪkə|
The name of Karl Wernicke (1848–1905), German neurologist, used in the possessive to designate: a. A neurological disorder in which there is an inability to understand speech and, usually, to speak sensibly, caused by a lesion of Wernicke's area, an area of the cerebral cortex comprising parts of the temporal and parietal lobes.
1887Vickery & Knapp tr. Strümpell's Text-bk. Med. 679 The word, when it is heard, may fail to call up the appropriate mental image. Kussmaul has given this condition the name of word deafness (Wernicke's sensory aphasia). The patient is not really deaf, for he hears everything, but he no longer understands what he hears, and has forgotten what the words signify. 1907Practitioner Oct. 545 In the Aphasia of Broca..the cases..closely resemble those of Wernicke's aphasia, with the difference that, in Broca's aphasia, the patient cannot speak. 1908A. Gordon Dis. Nervous Syst. vii. 118 Pierre Marie..holds that aphasia..is caused by a lesion in the lenticular nucleus and in Wernicke's zone; the latter comprises the following portions: supra-marginal gyrus, angular gyrus, the posterior portions of the first two temporal convolutions. 1965[see logorrhœa, logorrhea]. 1976New Yorker 15 Nov. 152/2 There are two areas of the cortex that have been shown to be directly involved in speaking. Those areas—known since the late nineteenth century as Broca's area and Wernicke's area— are on the side of the brain (usually the left) that is dominant for speech. 1979Sci. Amer. Sept. 161/1 In Wernicke's aphasia speech is phonetically and even grammatically normal, but it is semantically deviant.
b. An encephalopathy caused by vitamin B1 deficiency and characterized by mental confusion and uncontrolled movements, esp. of the eyes. So Wernicke–Korsakoff [see Korsakoff], applied to Wernicke's syndrome and Korsakoff's syndrome when both are present in an individual.
1910E. E. Southard in Osler & McCrae Syst. Med. VII. xiii. 631 (heading) Hemorrhagic superior poliencephalitis (Wernicke's disease). Ibid., The non-alcoholic and the alcoholic forms of Wernicke's disease are considered. 1939Jrnl. Path. & Bacteriol. XLVIII. 259 We suggest therefore that, as in chronic alcoholism so in pregnancy, B1 deficiency may play a part in producing Wernicke's encephalopathy as well as polyneuritis. 1966Trans. Amer. Neurol. Assoc. XCI. 31 The Wernicke–Korsakoff syndrome is..both a clinical and a pathological entity. 1978Sci. Amer. Oct. 76/3 The Wernicke-Korsakoff syndrome is a neurological disorder that begins with an acute phase characterized by palsy and poor muscular coordination; with treatment the acute phase gives way to a chronic phase, Korsakoff's psychosis, characterized by severe amnesia. |