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单词 mefenamic
释义 mefenamic, a. Pharm.|mɛfɪˈnæmɪk|
[f. methyl- + fen- (alteration of phen-) + amino- + -ic.]
mefenamic acid, a drug which inhibits prostaglandin synthesis and is used as an anti-inflammatory agent and analgesic; 2-[(2,3-dimethylphenyl)amino]benzoic acid, C15H15NO2 .
1962Jrnl. Pharmacol. & Exper. Therap. CXXXVIII. 405/1 N-(2,3-xylyl)anthranilic acid (CI-473; mefenamic acid), prepared by the copper-catalyzed condensation of o-chlorobenzoic acid and 2,3-dimethylaniline, has a molecular weight of 241.3.1967New Scientist 27 Apr. 217/3 Anti-inflammatory drugs such as phenylbutazone, mefenamic acid and flufenamic acid.1977Lancet 11 June 1239/2 Other pharmacological agents which might be released into the uterus to reduce the bleeding and pain include..the prostaglandin-synthetase inhibitors, mefenamic acid and flufenamic acid.1987M. J. Neal Med. Pharmacol. xxviii. 63/2 Fenamates (e.g. mefenamic acid) have the disadvantage of causing diarrhoea.
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