释义 |
mefenamic, a. Pharm.|mɛfɪˈnæmɪk| [f. methyl- + fen- (alteration of phen-) + amino- + -ic.] mefenamic acid, a drug which inhibits prostaglandin synthesis and is used as an anti-inflammatory agent and analgesic; 2-[(2,3-dimethylphenyl)amino]benzoic acid, C15H15NO2 .
1962Jrnl. Pharmacol. & Exper. Therap. CXXXVIII. 405/1 N-(2,3-xylyl)anthranilic acid (CI-473; mefenamic acid), prepared by the copper-catalyzed condensation of o-chlorobenzoic acid and 2,3-dimethylaniline, has a molecular weight of 241.3. 1967New Scientist 27 Apr. 217/3 Anti-inflammatory drugs such as phenylbutazone, mefenamic acid and flufenamic acid. 1977Lancet 11 June 1239/2 Other pharmacological agents which might be released into the uterus to reduce the bleeding and pain include..the prostaglandin-synthetase inhibitors, mefenamic acid and flufenamic acid. 1987M. J. Neal Med. Pharmacol. xxviii. 63/2 Fenamates (e.g. mefenamic acid) have the disadvantage of causing diarrhoea. |