释义 |
methysergide Pharm.|mɛθɪˈsɜːdʒaɪd| [f. meth- + lysergic a. + amide.] 1-Methyl-d-lysergic acid butanolamide, C21H28N3O2, a serotonin antagonist that is administered, usu. in the form of its maleate, in the prophylaxis of recurrent migraine.
1962Amer. Jrnl. Med. Sci. CCXLIII. 152/1 Fifty-seven patients..were treated with antiserotonin agent, methysergide (UML-491). 1962Daily Tel. 30 July 11/6 Methysergide (Deseril), is being tested as a preventive against chronic forms of migraine. 1968J. H. Burn Lect. Notes Pharmacol. (ed. 9) 30 In some patients methysergide causes dizziness and nausea and produces aching in the legs. |