| 释义 |
pentazocine Pharm.|pɛnˈtæzəʊsiːn|
[f. pentane + azo- + -ocine (f. octa- + -ine5).]
A tricyclic heterocyclic compound that is a non-addictive analgesic, given as the hydrochloride in tablet form or as the lactate by injection; 1,2,3,4,5,6-hexahydro-8-hydroxy-6,11-dimethyl-3-(3-methyl-2-butenyl)-2,6-methano-3-benzazocine, C19H27NO.
1964Jrnl. Pharmacol. & Exper. Therap. CXLIII. 142/1 (caption) Compound II has been assigned the generic name ‘pentazocine’ and Compound IV, ‘cyclazocine’. 1967Observer 5 Mar. 13/1 Pentazocine, which in pain-killing potency falls between morphine and pethidine, becomes available in an injectable form (under the name Fortral) on 5 April. 1974M. C. Gerald Pharmacol. xiii. 248 Pentazocine is an effective analgesic agent that also possesses modest narcotic antagonistic properties. 1977Sci. Amer. Mar. 47/2 The prototype is pentazocine (Talwin), which is widely used in the U.S. and is the only powerful opiate analgesic that is not subject to stringent ‘dangerous drug’ regulations. |