| 释义 |
pyocyanase Med.|paɪəʊˈsaɪəneɪz|
[a. G. pyocyanase (Emmerich & Löw 1899, in Zeitschr. f. Hygiene u. Infektionskrankheiten XXXI. 10), f. mod.L. pyocyan-eus (f. Gr. πύο-ν pus + κυάνεος dark blue), former specific epithet of the source bacterium + -ase -ase.]
An antibiotic preparation, orig. thought to be an enzyme, which was obtained from cultures of the bacterium Pseudomonas aeruginosus and was formerly used to treat a number of infections, esp. diphtheria.
1900Jrnl. Chem. Soc. LXXVIII. ii. 159 Thus pyocyanase, the enzyme of Bacillus pyocyaneus, destroys the deadly effect of the diphtheria toxin. 1908Lancet 21 Mar. 899/1 If pyocyanase came in contact with leucocytes, their plasma was dissolved so that the granules and the nuclei only remained and these were..immobilised. 1949H. W. Florey et al. Antibiotics I. i. 24 After 1914 the mention of pyocyanase for clinical use almost entirely disappeared from the literature. 1969Listener 5 June 781/1 The experiments of Florey and Chain on pyocyanase..went to show that pyocyanase was a complicated mixture of substances, all equally poisonous to microbes and to mice. |