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单词 clonal selection theory
释义

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clonal selection theory
clonal selection theory n. Immunology the (widely accepted) theory that the immune response to an antigen is dependent upon reaction of the antigen with pre-existing specific receptors on a small number of lymphocytes which then undergo clonal proliferation.
ΚΠ
1959 F. M. Burnet (title) The clonal selection theory of acquired immunity.
1984 M. J. Taussig Processes in Pathol. & Microbiol. (ed. 2) ii. 184 According to the clonal selection theory.., tolerance results from the death of antigen-sensitive cells.
2000 Immunol. Rev. 176 10/2 How the multiple and structurally diverse antigens could fulfill this task for the BCR [= B-cell antigen receptor] is unknown, and we regard this as an unsolved problem of Burnet's clonal selection theory.
extracted from clonaladj.
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