| 单词 | endogenous cannabinoid |
| 释义 | > as lemmasendogenous cannabinoid Any of a group of substances including cannabinol, cannabidiol, and other structurally related compounds of natural and synthetic origin. In later use also (in full endogenous cannabinoid): any of a group of compounds, typically derivatives of arachidonic acid, which occur naturally in animals and are able to bind to the same cellular receptors as those which bind plant cannabinoids. ΘΚΠ the world > matter > chemistry > organic chemistry > organic compounds > [noun] > cyclic compounds > tricyclic compounds xanthene1898 thioxanthene1911 psoralen1933 lysergic acid1934 cannabinoid1967 1967 R. Mechoulam & Y. Gaoni in Fortschritte der Chemie Organischer Naturstoffe 25 178 We propose the term cannabinoids for the group of C21-compounds typical of and present in C. sativa, as well as for their analogs and transformation products. 1974 M. C. Gerald Pharmacol. xviii. 339 Cannabis contains a group of closely related compounds that are collectively termed cannabinoids... These compounds do not contain a nitrogen atom and, therefore, are not alkaloids. 2000 J. Mann Murder, Magic, & Med. (rev. ed.) iii. 85 Raphael Mechoulam isolated the substance anandamide in 1992 from pig brain, and showed that this substance bound to the cannabinoid receptor. It was thus an endogenous mammalian cannabinoid. 2010 Wall St. Jrnl. 17 July a14/4 Spice, a synthetic cannabinoid that is similar to cannabis, became popular in Europe in 2008 and was subsequently banned. < as lemmas |
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