androstenedionen.

/ˌændrɒstiːnˈdaɪəʊn/

Etymology: < German Androstendion (coined by Ruzicka and Wettstein 1935, in Helv. Chim. Acta 18 988): see androsterone n., -ene comb. form, -dione suffix.

Physiol.

An androgenic steroid, C₁₉H₂₆O₂, from which testosterone and certain oestrogens are derived in humans.

ΚΠ

1935 Nature 17 Aug. 259/1 The table clearly shows the high activity of androstendione [sic] on the seminal vesicles and the penis.

1959 S. L. Simpson Major Endocrine Disorders (ed. 3) ii. 80 The two important adrenal androgens in man are 11β-hydroxy Δ⁴-androstene-3-17-dione and Δ⁴-androstenedione.

1964 L. C. Martin Clin. Endocrinol. (ed. 4) viii. 263 The normal ovarian theca-cell contains all the enzymes needed for the conversion of progesterone to oestradiol, an intermediate stage being the substance androstenedione.

1988 L. Stryer Biochemistry (ed. 3) xxiii. 568 The side chain consisting of C-20 and C-21 is then cleaved to yield androstenedione, an androgen.

This entry has not yet been fully updated (first published 1997; most recently modified version published online November 2010).

单词	androstenedione
释义	androstenedionen. /ˌændrɒstiːnˈdaɪəʊn/ Etymology: < German Androstendion (coined by Ruzicka and Wettstein 1935, in Helv. Chim. Acta 18 988): see androsterone n., -ene comb. form, -dione suffix. Physiol. An androgenic steroid, C₁₉H₂₆O₂, from which testosterone and certain oestrogens are derived in humans. ΚΠ 1935 Nature 17 Aug. 259/1 The table clearly shows the high activity of androstendione [sic] on the seminal vesicles and the penis. 1959 S. L. Simpson Major Endocrine Disorders (ed. 3) ii. 80 The two important adrenal androgens in man are 11β-hydroxy Δ⁴-androstene-3-17-dione and Δ⁴-androstenedione. 1964 L. C. Martin Clin. Endocrinol. (ed. 4) viii. 263 The normal ovarian theca-cell contains all the enzymes needed for the conversion of progesterone to oestradiol, an intermediate stage being the substance androstenedione. 1988 L. Stryer Biochemistry (ed. 3) xxiii. 568 The side chain consisting of C-20 and C-21 is then cleaved to yield androstenedione, an androgen. This entry has not yet been fully updated (first published 1997; most recently modified version published online November 2010). < n.1935
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