folinicadj.
/fə(ʊ)ˈlɪnɪk//fɒˈlɪnɪk/ Biochemistry.
folinic acid n. a derivative of folic acid, believed to be the form in which the latter acts as a coenzyme.
ΚΠ
1949 T. J. Bond et al. in Jrnl. Amer. Chem. Soc. LXXI. 3852/2 On the basis of structure and functional relationship to folic acid, this active principle has been termed folinic acid.
1962 New Scientist 17 May 364/3 To counter~act the damaging effects of the methotrexate that spilled over into the general circulation, a biological antagonist, folinic acid (leucovorin), was injected intramuscularly.
1966 E. S. West et al. Textbk. Biochem. (ed. 4) xviii. 814 Folinic acid, citrovorum factor (CF), and leucovorin are names for a naturally occurring derivative of folic acid... It is N5-formyl-5,6,7,8-tetrahydropteroylglutamic acid.
This entry has not yet been fully updated (first published 1972; most recently modified version published online March 2019).
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adj.1949