immunogenn.

Brit.

/ˈɪmjᵿnəʊdʒɛn/,

/ɪˈmjuːnəʊdʒɛn/, U.S.

/ˈɪmjənoʊˌdʒɛn/,

/ᵻˈmjunoʊˌdʒɛn/

Origin: Formed within English, by compounding. Etymons: immuno- comb. form, -gen comb. form.

Etymology: < immuno- comb. form + -gen comb. form.

Medicine and Biology.

1. Any of various preparations of bacteria used for immunization, typically made by washing the bacterial cells and believed to consist of antigens located in the ectoplasm. Now rare.

ΘΚΠ

the world > life > biology > substance > process stimulators or inhibitors > immunogen or antigen > [noun] > removed by washing

immunogen1923

1923 Trade Marks Jrnl. 31 Jan. 181 Immunogen... Parke Davis & Company.

1923 Lancet 30 June 1305/1 We shall, no doubt, hear advocates on behalf of..gonococcus ‘immunogen’ so prepared as to render the cell structure more easily digested by the tissues and containing some of the specific endotoxin in solution.

1926 T. Horder & N. S. Ferry in Brit. Med. Jrnl. 31 July 179/2 As it would appear from these results..that the antigenic or immunizing portion of the bacterial cell is more ectoplasmic than endoplasmic in origin, it is proposed to call this type of antigen an ‘ectoantigen’, and for products prepared in such a manner as to contain only this ectoantigen the designation ‘immunogens’ is suggested, to distinguish them from other antigenic products already in use.

1929 J. W. Bigger Handbk. Bacteriol. (ed. 2) vi. 88 ‘Immunogens’ (Horder & Ferry) are the washings of bacteria. They are stated to contain the immunizing substances of bacteria without the toxins.

1934 Jrnl. Amer. Med. Assoc. 22 Sept. 939/2 Immunogen (Parke, Davis & Co.) may be a mixture of antigenic substances. It is not on the accepted list of New and Nonofficial Remedies.

1944 Science 16 June 497/2 It was found that the immunogen responsible for this immunity was easily removed from the organisms by solution in dilute HCl.

2. Any substance capable of eliciting an immune response.

ΘΚΠ

the world > life > biology > substance > process stimulators or inhibitors > immunogen or antigen > [noun]

antigen1908

isoantigen1936

rhesus antigen1946

immunogen1959

alloantigen1964

1959 A. D. Bussard in Ann. Rev. Microbiol. 13 280 The following terms will be used..in the course of this review: immunogenicity: ability of a substance to direct the formation of a specific antibody; antigenicity: ability of a substance to react with an antibody under a given set of conditions. An immunogen is a substance exhibiting immunogenicity and an antigen, a substance exhibiting antigenicity.

1971 S. O. Freedman et al. Clin. Immunol. i. 3 Although the terms immunogen and antigen are frequently used interchangeably, they are not necessarily synonymous... Employed correctly, the term immunogen specifies that a substance acts at the afferent limb of the immune response.

1987 Mountain Democrat (Placerville, Ca.) 8 July a13/3 The immunization is given in a single injection in which the immunogen is emulsified in a thick oil-water mixture.

2006 Jrnl. Immunol. Methods 317 1 One major obstacle in antibody production is the lack of highly purified immunogen.

This entry has been updated (OED Third Edition, June 2008; most recently modified version published online March 2022).

单词	immunogen
释义	immunogenn. Brit. /ˈɪmjᵿnəʊdʒɛn/, /ɪˈmjuːnəʊdʒɛn/, U.S. /ˈɪmjənoʊˌdʒɛn/, /ᵻˈmjunoʊˌdʒɛn/ Origin: Formed within English, by compounding. Etymons: immuno- comb. form, -gen comb. form. Etymology: < immuno- comb. form + -gen comb. form. Medicine and Biology. 1. Any of various preparations of bacteria used for immunization, typically made by washing the bacterial cells and believed to consist of antigens located in the ectoplasm. Now rare. ΘΚΠ the world > life > biology > substance > process stimulators or inhibitors > immunogen or antigen > [noun] > removed by washing immunogen1923 1923 Trade Marks Jrnl. 31 Jan. 181 Immunogen... Parke Davis & Company. 1923 Lancet 30 June 1305/1 We shall, no doubt, hear advocates on behalf of..gonococcus ‘immunogen’ so prepared as to render the cell structure more easily digested by the tissues and containing some of the specific endotoxin in solution. 1926 T. Horder & N. S. Ferry in Brit. Med. Jrnl. 31 July 179/2 As it would appear from these results..that the antigenic or immunizing portion of the bacterial cell is more ectoplasmic than endoplasmic in origin, it is proposed to call this type of antigen an ‘ectoantigen’, and for products prepared in such a manner as to contain only this ectoantigen the designation ‘immunogens’ is suggested, to distinguish them from other antigenic products already in use. 1929 J. W. Bigger Handbk. Bacteriol. (ed. 2) vi. 88 ‘Immunogens’ (Horder & Ferry) are the washings of bacteria. They are stated to contain the immunizing substances of bacteria without the toxins. 1934 Jrnl. Amer. Med. Assoc. 22 Sept. 939/2 Immunogen (Parke, Davis & Co.) may be a mixture of antigenic substances. It is not on the accepted list of New and Nonofficial Remedies. 1944 Science 16 June 497/2 It was found that the immunogen responsible for this immunity was easily removed from the organisms by solution in dilute HCl. 2. Any substance capable of eliciting an immune response. ΘΚΠ the world > life > biology > substance > process stimulators or inhibitors > immunogen or antigen > [noun] antigen1908 isoantigen1936 rhesus antigen1946 immunogen1959 alloantigen1964 1959 A. D. Bussard in Ann. Rev. Microbiol. 13 280 The following terms will be used..in the course of this review: immunogenicity: ability of a substance to direct the formation of a specific antibody; antigenicity: ability of a substance to react with an antibody under a given set of conditions. An immunogen is a substance exhibiting immunogenicity and an antigen, a substance exhibiting antigenicity. 1971 S. O. Freedman et al. Clin. Immunol. i. 3 Although the terms immunogen and antigen are frequently used interchangeably, they are not necessarily synonymous... Employed correctly, the term immunogen specifies that a substance acts at the afferent limb of the immune response. 1987 Mountain Democrat (Placerville, Ca.) 8 July a13/3 The immunization is given in a single injection in which the immunogen is emulsified in a thick oil-water mixture. 2006 Jrnl. Immunol. Methods 317 1 One major obstacle in antibody production is the lack of highly purified immunogen. This entry has been updated (OED Third Edition, June 2008; most recently modified version published online March 2022). < n.1923
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