oxoglutaraten.

Brit.

/ˌɒksəʊˈɡluːtəreɪt/, U.S.

/ˌɑksoʊˈɡludəˌreɪt/

Origin: Formed within English, by derivation. Etymons: oxo- comb. form, glutaric adj. at glut- comb. form , -ate suffix⁴.

Etymology: < oxo- comb. form + glutar- (in glutaric adj. at glut- comb. form ) + -ate suffix⁴. Compare oxoglutaric adj.

Biochemistry.

In full α-oxoglutarate (or 2-oxoglutarate). The anion of α-oxoglutaric acid, which is an important intermediate in amino acid metabolism and the Krebs cycle; α-ketoglutarate; (also) a salt of this acid.

ΚΠ

1945 Jrnl. Amer. Chem. Soc. 67 60 Condensation of these esters using sodium yielded diethyl-β-carbethoxy-α-oxoglutarate from which α-oxoglutaric acid was obtained on hydrolysis and decarboxylation.

1966 Adv. in Enzyme Regulation 4 317 It is considered that the oxidation of isocitrate to 2-oxoglutarate is more sensitive to ammonia than the other dehydrogenases in the TCA cycle.

1992 C. A. Smith & E. J. Wood Biosynthesis iii. 59 Alanine enters hepatic mitochondria and is transaminated with α-oxoglutarate to produce glutamate and pyruvate.

2002 European Jrnl. Biochem. 269 5004 Another, carbon-centered, radical was trapped in anaerobic reaction of the complex with 2-oxoglutarate and CoA by 5,5′-dimethyl-1-pyrroline-N-oxide (DMPO).

This is a new entry (OED Third Edition, March 2005; most recently modified version published online March 2022).

单词	oxoglutarate
释义	oxoglutaraten. Brit. /ˌɒksəʊˈɡluːtəreɪt/, U.S. /ˌɑksoʊˈɡludəˌreɪt/ Origin: Formed within English, by derivation. Etymons: oxo- comb. form, glutaric adj. at glut- comb. form , -ate suffix⁴. Etymology: < oxo- comb. form + glutar- (in glutaric adj. at glut- comb. form ) + -ate suffix⁴. Compare oxoglutaric adj. Biochemistry. In full α-oxoglutarate (or 2-oxoglutarate). The anion of α-oxoglutaric acid, which is an important intermediate in amino acid metabolism and the Krebs cycle; α-ketoglutarate; (also) a salt of this acid. ΚΠ 1945 Jrnl. Amer. Chem. Soc. 67 60 Condensation of these esters using sodium yielded diethyl-β-carbethoxy-α-oxoglutarate from which α-oxoglutaric acid was obtained on hydrolysis and decarboxylation. 1966 Adv. in Enzyme Regulation 4 317 It is considered that the oxidation of isocitrate to 2-oxoglutarate is more sensitive to ammonia than the other dehydrogenases in the TCA cycle. 1992 C. A. Smith & E. J. Wood Biosynthesis iii. 59 Alanine enters hepatic mitochondria and is transaminated with α-oxoglutarate to produce glutamate and pyruvate. 2002 European Jrnl. Biochem. 269 5004 Another, carbon-centered, radical was trapped in anaerobic reaction of the complex with 2-oxoglutarate and CoA by 5,5′-dimethyl-1-pyrroline-N-oxide (DMPO). This is a new entry (OED Third Edition, March 2005; most recently modified version published online March 2022). < n.1945
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