| 单词 | sonic hedgehog |
| 释义 | > as lemmassonic hedgehog Genetics and Embryology. [With allusion to the bristly shape of Drosophila mutants at this locus.] A gene originally identified in the fruit fly Drosophila melanogaster which encodes a protein involved in the determination of segmental polarity and cell-to-cell signalling during embryonic development and metamorphosis; the protein encoded by this gene. Also (in full sonic hedgehog): the homologous gene or protein in various vertebrate species.The gene is commonly denoted by the word in italics, the protein by the word in roman and with a capital initial. ΘΚΠ the world > life > biology > biological processes > genetic activity > genetic components > [noun] > gene > types of gene sex determinant1902 sex determiner1909 inhibitor1911 multiple factor1912 modifier1915 autosomal dominant1919 autosomal recessive1919 scute1923 gene1925 suppressor1928 rate gene1932 dominigene1938 buffer1939 polygene1941 switch gene1942 mutator1943 oligogene1943 sickle cell gene1946 supergene1949 ob1950 obese1950 regulator1960 regulator gene1960 regulatory gene1960 enhancer1967 oncogene1969 virogene1969 hedgehog1980 1980 C. Nüsslein-Volhard & E. Wieschaus in Nature 30 Oct. 796/1 Six such loci have been identified. Three loci, for fused, wingless..and cubitus interruptus, were previously known whereas gooseberry, hedgehog and patch are new. 1993 R. Riddle et al. in Cell 75 1401/1 We have isolated a vertebrate gene, Sonic hedgehog, related to the Drosophila segment polarity gene hedgehog,..that is capable of polarizing limbs in grafting experiments. 1997 New Scientist 5 Apr. 24/1 Injections of a protein called sonic hedgehog into the brains of people with Parkinson's disease may be able to restore the number of dopamine-producing cells in the brain. 1998 Proc. National Acad. Sci. U.S.A. 95 9937/1 One possibility is that Cyclops activity may be required in addition to Hedgehog signaling to antagonize dorsalizing factors. < as lemmas |
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