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单词 villin
释义

villinn.

/ˈvɪlɪn/
Etymology: < vill- (in villus n.) + -in suffix1.
Biochemistry.
A protein found in the microvilli of the small intestine and involved in the calcium-dependent cleaving of actin microfilaments, and hence in the regulation of cell motility.
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the world > life > biology > substance > proteins > [noun]
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1979 Bretscher & Weber in Proc. National Acad. Sci. U.S.A. 76 2321/2 Here we describe the isolation of the 95,000 molecular weight protein, which we call villin, and show that it is immunologically and functionally distinct from α-actinin.
1987 Nature 16 Apr. 646/2 Small regions of the synapsin sequence are 40–50 per cent identical to villin, a calcium-dependent actin severing and bundling protein, and profilin, a protein that sequesters actin monomers.
1988 P. W. Kuchel et al. Schaum's Outl. Theory & Probl. Biochem. v. 125 Villin, a major protein of the microvilli of the intestinal brush border..will also fragment (sever) the filament.
This entry has not yet been fully updated (first published 1993; most recently modified version published online June 2018).
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n.1979
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