having an extra chromosome in the haploid state that is homologous to an existing chromosome in this set
Derived forms
disomy (diˈsomy)
noun
Examples of 'disomic' in a sentence
disomic
Disomic littermates provided karyotype controls for trisomic pups.
Angela L Rachubinski, Shannon K Crowley, John R Sladek, Kenneth N Maclean, KimberlyB Bjugstad 2012, 'Effects of neonatal neural progenitor cell implantation on adult neuroanatomy andcognition in the Ts65Dn model of Down syndrome.', PLoS ONEhttp://europepmc.org/articles/PMC3338504?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
F45 colonies display complex “fluffy” morphologies, while the disomic colonies are smooth, resembling laboratory strains.
Gareth A. Cromie, Zhihao Tan, Michelle Hays, Eric W. Jeffery, Aimée M. Dudley 2017, 'Dissecting Gene Expression Changes Accompanying a Ploidy-Based Phenotypic Switch',G3: Genes, Genomes, Geneticshttp://g3journal.org/lookup/doi/10.1534/g3.116.036160. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Gene expression analysis of cultured keratinocytes revealed upregulation of several trisomic and disomic genes may contribute to this hyperproliferation.
Annan Yang, Duane Currier, Jennifer L Poitras, Roger H Reeves 2016, 'Increased Skin Tumor Incidence and Keratinocyte Hyper-Proliferation in a Mouse Modelof Down Syndrome.', PLoS ONEhttp://europepmc.org/articles/PMC4708994?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Further, short inverted sequences are present at the boundary of the disomic spacer and the inverted duplication.
Karen E Hermetz, Scott Newman, Karen N Conneely, Christa L Martin, Blake C Ballif,Lisa G Shaffer, Jannine D Cody, M Katharine Rudd 2014, 'Large inverted duplications in the human genome form via a fold-back mechanism.',PLoS Geneticshttp://europepmc.org/articles/PMC3907307?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
A survey of environmental and clinical isolates maintained in culture revealed few occurrences of disomic chromosomes.
Hu Guanggan, Wang Joyce, Choi Jaehyuk, Jung Won, Liu Iris, Litvintseva Anastasia P,Bicanic Tihana, Aurora Rajeev, Mitchell Thomas G, Perfect John R, Kronstad James W 2011, 'Variation in chromosome copy number influences the virulence of Cryptococcus neoformansand occurs in isolates from AIDS patients', BMC Genomicshttp://www.biomedcentral.com/1471-2164/12/526. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Sequence analysis of breakpoint junctions reveals a normal-copy disomic spacer between inverted and non-inverted copies of the duplication.
Karen E Hermetz, Scott Newman, Karen N Conneely, Christa L Martin, Blake C Ballif,Lisa G Shaffer, Jannine D Cody, M Katharine Rudd 2014, 'Large inverted duplications in the human genome form via a fold-back mechanism.',PLoS Geneticshttp://europepmc.org/articles/PMC3907307?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)