Lutz-Splendore-Almeida disease


paracoccidioidomycosis

 [par″ah-kok-sid″e-oi″do-mi-ko´sis] an often fatal, chronic granulomatous disease caused by Paracoccidioides brasiliensis; it is endemic in Brazil and also occurs elsewhere in South and Central America and in arid regions of the southwestern United States. Infection primarily involves the lungs, but spreads to the skin, mucous membranes, lymph nodes, and internal organs. Amphotericin B is the specific drug used for treatment. Called also South American blastomycosis.

par·a·coc·cid·i·oi·do·my·co·sis

(par'ă-kok-sid'ē-oy'dō-mī-kō'sis), A chronic mycosis characterized by primary pulmonary lesions with dissemination to many visceral organs, conspicuous ulcerative granulomas of the buccal and nasal mucosa with extensions to the skin, and generalized lymphangitis; caused by Paracoccidioides brasiliensis. Synonym(s): Almeida disease, Lutz-Splendore-Almeida disease, paracoccidioidal granuloma, South American blastomycosis

Lutz-Splendore-Almeida disease

(loots-splen-dor'a-al-ma'da) [Adolfo. Lutz, Brazilian physician, 1855–1940; Alfonso Splendore, Italian physician, 1871–1953; Floriano Paulo de Almeida, Brazilian physician, 1898–1977] South American blastomycosis.

Almeida,

Floriano Paulo de, Brazilian physician, 1898–. Almeida disease - a chronic mycosis caused by Paracoccidioides brasiliensis. Synonym(s): paracoccidioidomycosisLutz-Splendore-Almeida disease - see under Lutz

Lutz,

Alfredo, Brazilian physician, 1855-1940. Lutz-Splendore-Almeida disease - a chronic mycosis caused by Paracoccidioides brasiliensis. Synonym(s): paracoccidioidomycosis

Splendore,

Alfonso, Brazilian physician, 1871-1953. Lutz-Splendore-Almeida disease - see under LutzSplendore-Hoeppli phenomenon - radiating or anular eosinophilic deposits of host-derived materials and possibly of parasite antigens, which form around fungi, helminths, or bacterial colonies in tissue.